Hereditary Cancer Genetic Testing

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Cancer Genetic Testing (CGx) DNA cancer testing.

Advanced Genomic testing is designed to help identify the DNA alterations that may be driving the growth of a specific cancer unique to you. DNA testing provides information to the physician for possible early detection and/or to design and identify treatments specifically designed to target those mutations.

Understanding Hereditary or Predisposition Cancer Genomics

Genetic testing analyzes specific inherited changes (mutations) in a person’s genetic make-up. Genetic
mutations may have different effects on a person’s health. Mutations that are harmful may increase a
person’s chance or risk of developing a disease such as cancer. Inherited mutations are thought to play a
role in 5-10% of all cancers*. These conditions are considered hereditary and appropriate genetic testing
may be used to determine an individual’s predisposition risk.
Germline DNA is the source of DNA for all other cells in the body. Some people inherit mutations in the
germline from their parents which then allows for the mutations to be passed to their children. There
are two classes of cellular genes: oncogenes and tumor suppressor genes. Often multiple genetic
mutations in a single individual are responsible for the development of hereditary cancers.

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Cancer research has identified more than 100 gene mutations that increase the risk for cancer. A persons DNA is the set of instructions to build and maintain an organism. Some changes in DNA may help fight cancer. Other changes can make a person more likely to develop cancer.

Genetic counseling and testing may be recommended for people who have had certain cancers or certain patterns of cancer in their family.

What Are Some Conditions Qualified for Genetic Cancer Testing?

Cancer genetic testing may help in the following ways

Identify a genetic change that may increase your risk for cancer

Detect and suggest proper treatment for a cancer early, when the remission and survival rates are best

Help your doctor and healthcare professionals choose the best treatments

Choose a cancer prevention strategy

Consider how cancer may affect reproductive options

Provide information about your risk for children having cancer